In response to the call of the Lazio Region “Strategic Projects – POR FESR 2014-2020”, FEA presented the project “ProPeople: Personalized therapeutic treatment of oncological pathologies through local release of drugs and high sensitivity monitoring”.
The ultimate goal is to develop an integrated therapeutic approach for the treatment of neoplastic diseases through
The use of local drug release systems
The "personalization" of the dosage of therapeutic agents
The monitoring of tumor markers.
In particular, the last two clinical activities will make use of the support of SERS technology to achieve a high detection sensitivity, while allowing the development and validation of ad hoc sensors as commercial / entrepreneurial output. This proposal is part of the “Life Sciences” Department, addressing a double priority theme “Oncology (including anticancer)” and “Advanced Biosensory for living environments, for food, for early diagnosis”, as reported in the Smart Specialization Strategy document of the Lazio Region.
The research theme will allow to achieve high scientific and practical purposes, favoring an advancement in the treatment of certain tumor pathologies that can be widely spread in international journals of medicine, pharmacology and biomedical engineering. Each of the partial objectives of which the project is composed represents in itself an innovative element in the treatment and evaluation of the post-operative course: the localized-release therapeutic device presents aspects of improvement compared to similar systems in terms of conformability and homogeneous diffusion on the site of interest, while the SERS sensors can be specially designed to optimize their use both to dose the drug and to detect tumor biomarkers.
The working group consists of a consortium made up of public, private and business research bodies in order to take care of every aspect of the project in a homogeneous and concrete way, both as regards scientific research and technology transfer.